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Exploring conformational stability (e.g., the AlphaFold2-RAVE approach for kinase loops). Multi-omics Integration: New frameworks like the AlphaFold2-RAVE approach for kinase loops).
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RCTD's likelihood model is defined on raw count data, not on log-normalized values. Ensure your input datasets use raw counts to prevent skewed statistical fitting and inaccurate cell type proportion estimates.
