Disable SMAA inside the game graphics settings. Instead, increase the resolution scaling inside your streaming tool (Virtual Desktop to 'High' or 'Godlike') to leverage the high physical pixel density of the Pico 4 pancake displays. Conclusion
Your Pico 4 needs to talk to your gaming PC. You have three main options for this connection, each with its own pros and cons. euro truck simulator 2 vr pico 4